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The drugs, acamprosate (marketing name: Campral) and naltrexone (ReVia) were found to help you those struggling in different phases of recovery. Acamprosate helped manage emotional triggers in those who had already stopped drinking, naltrexone helped manage cravings in heavy drinkers who are attempting to stop drinking or recently quit. Using two separate drugs to lose weight naturally can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the those who go through it one should err to the side of caution and allow the FDA do its job and demand some study be done so the public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies will be in business to make money and that they would say anything to keep people on their medications. Researchers found that participants investing in this drug for a year, lost weight within 4 weeks and have kept the body weight off through the 56 weeks of the study. Contrave is a combination in the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs which are made up of more than one active ingredient, which may make them far better and safer. Combo-pilling could be the newest fad or better yet the newest in the future under scrutiny and for that reason it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular is the fact that as of right now there aren't long term prescription weightloss pills that have been authorized by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be approved by the FDA. Seizures certainly are a side effect with Contrave and must not be taken in people with seizure disorders. The drug also can raise blood pressure and heartrate, and must not be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise hypertension and heart rate and must stop used in patients with uncontrolled high hypertension, as well as by anyone with heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients which has a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients towards the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. The most common side effects reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.